Copper preparations have a history of sterilization applications for more than 100 years, and no virus has been found to be resistant to them. It is one of the recommended varieties listed by the Ministry of Agriculture for pollution-free products. It is also a green and environmental protection fungicide advocated by European and American countries. The development of nanotechnology provides a broader market prospect for the application of copper hydroxide. The basic copper sulfate nanosheets have the small size effect of nanomaterials, the specific surface area increases sharply, the surface atoms and body atoms are equivalent, the surface atomic activity is greatly improved, and the free active copper ions are multiplied. Wettable powder of Basic Copper Sulphate nano flakes can be sprayed uniformly, has strong adhesion, is resistant to rain erosion, and has a long shelf life. The traditional Bordeaux liquid sprays a large amount, and the liquid drops drip into the ground to cause land alkalization. The basic copper sulfate nanobelt bactericide can replace the traditional Bordeaux liquid, and the sterilization effect has a qualitative leap.